Rnf135 | ring finger protein 135

GeneMGI:1919206Synonyms: 2410006N06Rik, U 2-3-0, +2 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Digestive/alimentary Behavior/neurological Skeleton

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal skin morphology	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
decreased grip strength	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	1.22x10^-6
small ovary	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
small uterus	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal stomach morphology	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal sternum morphology	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Late adult	1.97x10^-7
abnormal stomach morphology	1 supporting dataset	Rnf135^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf135.

Associated images

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Histopathology

There is no histopathology data found for Rnf135.

IMPC related publications

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External links

No external links available for Rnf135.

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*Rnf135^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Rnf135^{tm17(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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