Ist1 | increased sodium tolerance 1 homolog (yeast)

GeneMGI:1919205Synonyms: 2400003C14Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Hearing/vestibular/ear Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased heart rate	1 supporting dataset	Ist1^em1(IMPC)J	heterozygote	Early adult	7.96x10^-5
abnormal auditory brainstem response	1 supporting dataset	Ist1^em1(IMPC)J	heterozygote	Early adult	3.71x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Ist1^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ist1.

Associated images

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Histopathology

There is no histopathology data found for Ist1.

IMPC related publications

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External links

No external links available for Ist1.

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*Ist1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Ist1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ist1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ist1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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