Cers5 | ceramide synthase 5

GeneMGI:1919199Synonyms: Trh4, CerS5, +2 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



abnormal bone structure	1 supporting dataset	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	1.11x10^-11
decreased thigmotaxis	2 supporting datasets	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	5.01x10^-5
decreased bone mineral density	1 supporting dataset	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	9.05x10^-8
abnormal motor coordination/balance	1 supporting dataset	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	2.07x10^-5
decreased exploration in new environment	1 supporting dataset	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	5.39x10^-8
decreased bone mineral content	2 supporting datasets	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	1.04x10^-8
increased circulating sodium level	1 supporting dataset	Cers5^{tm2b(KOMP)Mbp}	homozygote	Early adult	2.87x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Cers5.

Associated images

Loading...

Histopathology

There is no histopathology data found for Cers5.

IMPC related publications

Loading...

External links

No external links available for Cers5.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Cers5^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cers5^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Cers5^{tm2a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cers5^{tm2b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cers5^{tm2e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

My Genes