Cars2 | cysteinyl-tRNA synthetase 2, mitochondrial

GeneMGI:1919191Synonyms: 2310051N18Rik, 2410044A07Rik, +1 more

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Behavior/neurological Cardiovascular system Mortality/aging

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Cars2^em1(IMPC)Bay	heterozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Cars2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Cars2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
limb grasping	1 supporting dataset	Cars2^em1(IMPC)Bay	heterozygote	Early adult	2.03x10^-16
embryonic lethality prior to tooth bud stage	1 supporting dataset	Cars2^em1(IMPC)Bay	homozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Cars2^em1(IMPC)Bay	heterozygote	E12.5	N/A ^*
hemorrhage	1 supporting dataset	Cars2^em1(IMPC)Bay	heterozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Cars2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Cars2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Cars2^em1(IMPC)Bay	heterozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cars2.

Associated images

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Histopathology

There is no histopathology data found for Cars2.

IMPC related publications

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External links

No external links available for Cars2.

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*Cars2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Cars2^{tm379124(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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