Fam219a | family with sequence similarity 219, member A

GeneMGI:1919151Synonyms: 2310028H24Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Respiratory system Hematopoietic system Skeleton Craniofacial

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal tooth morphology1 supporting datasetFam219aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased body weight1 supporting datasetFam219aem1(IMPC)CcpczhomozygoteEarly adult3.21x10-5 
increased airway resistance1 supporting datasetFam219aem1(IMPC)CcpczhomozygoteEarly adult5.98x10-5 
abnormal thymus morphology1 supporting datasetFam219aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetFam219aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetFam219aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam219aem1(IMPC)CcpczExon Deletionmouse
Fam219atm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Fam219atm36019(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Fam219atm36019(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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