Apmap | adipocyte plasma membrane associated protein

GeneMGI:1919131Synonyms: 2310001A20Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Craniofacial

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	1.75x10^-5
decreased grip strength	2 supporting datasets	Apmap^em1(IMPC)J	homozygote	Late adult	8.11x10^-6
increased circulating HDL cholesterol level	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	7.44x10^-7
increased circulating phosphate level	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	2.31x10^-7
iris synechia	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	1.16x10^-7
abnormal lens morphology	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	2.37x10^-7
abnormal mouth morphology	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	3.69x10^-5
abnormal startle reflex	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	1.94x10^-6
increased total body fat amount	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	3.2x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Apmap^em1(IMPC)J	homozygote	Late adult	2.28x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Apmap.

Associated images

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Histopathology

There is no histopathology data found for Apmap.

IMPC related publications

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External links

No external links available for Apmap.

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*Apmap^em1(IMPC)J*	Exon Deletion	‌	mouse
*Apmap^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Apmap^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Apmap^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Apmap^{tm44207(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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