Pdia6 | protein disulfide isomerase associated 6
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Adipose tissue Hematopoietic system Behavior/neurological Mortality/aging
16 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 1 supporting dataset | Pdia6tm1b(EUCOMM)Hmgu | heterozygote | Late adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pdia6tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal gait | 1 supporting dataset | Pdia6tm1b(EUCOMM)Hmgu | heterozygote | Late adult | 5.2x10-5 | ||
| decreased CD4-positive NK T cell number | 1 supporting dataset | Pdia6tm1b(EUCOMM)Hmgu | heterozygote | Late adult | 1x10-4 | ||
| increased total body fat amount | 1 supporting dataset | Pdia6tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.35x10-5 | ||
| enlarged thyroid gland | 1 supporting dataset | Pdia6tm1b(EUCOMM)Hmgu | heterozygote | Late adult | N/A * |
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External links
No external links available for Pdia6.
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| Pdia6tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Pdia6tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pdia6tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |