Syce2 | synaptonemal complex central element protein 2

GeneMGI:1919096Synonyms: 1700013H19Rik

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Integument Endocrine/exocrine gland Adipose tissue Growth/size/body region Behavior/neurological Skeleton Renal/urinary system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	2 supporting datasets	Syce2^em1(IMPC)Tcp	homozygote	Early adult	4.34x10^-13
decreased bone mineral density	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	1.38x10^-10
male infertility	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
female infertility	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased bone mineral content	2 supporting datasets	Syce2^em1(IMPC)Tcp	homozygote	Early adult	8.14x10^-15
decreased grip strength	2 supporting datasets	Syce2^em1(IMPC)Tcp	homozygote	Early adult	1.49x10^-6
small epididymis	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Syce2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Syce2.

Associated images

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Histopathology

There is no histopathology data found for Syce2.

IMPC related publications

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External links

No external links available for Syce2.

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*Syce2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Syce2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Syce2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Syce2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Syce2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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