Lancl2 | LanC (bacterial lantibiotic synthetase component C)-like 2

GeneMGI:1919085Synonyms: 1700003F10Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Growth/size/body region Cardiovascular system Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetLancl2tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetLancl2tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal coat/hair pigmentation3 supporting datasetsLancl2tm2b(KOMP)WtsihomozygoteEarly adult4.76x10-6 
abnormal kidney morphology1 supporting datasetLancl2tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetLancl2tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lancl2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lancl2tm2b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Lancl2tm41859(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Lancl2tm41859(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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