Zbtb43 | zinc finger and BTB domain containing 43

GeneMGI:1919084Synonyms: Zfp297b, 1700010E06Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

hyperactivity5 supporting datasetsZbtb43tm1b(KOMP)MbphomozygoteEarly adult8.66x10-19 
abnormal behavior1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult6.82x10-12 
increased circulating alanine transaminase level1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult5.37x10-11 
persistence of hyaloid vascular system1 supporting datasetZbtb43tm1b(KOMP)MbpheterozygoteEarly adult2.95x10-5 
decreased thigmotaxis2 supporting datasetsZbtb43tm1b(KOMP)MbphomozygoteEarly adult6.82x10-12 
impaired pupillary reflex1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult1.23x10-10 
decreased circulating serum albumin level1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult2.43x10-8 
increased lean body mass1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult6.87x10-5 
increased mean corpuscular volume1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult1.22x10-6 
decreased circulating glucose level1 supporting datasetZbtb43tm1b(KOMP)MbphomozygoteEarly adult7.34x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zbtb43tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zbtb43tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Zbtb43tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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