Pitpnc1 | phosphatidylinositol transfer protein, cytoplasmic 1

GeneMGI:1919045Synonyms: RDGB-BETA, C330017I21Rik, +3 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased circulating glucose level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Early adult	2.97x10^-6
increased circulating cholesterol level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Late adult	2.27x10^-6
increased lean body mass	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Early adult	9.68x10^-5
increased circulating serum albumin level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Early adult	8.83x10^-5
increased circulating creatine kinase level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Early adult	1.6x10^-10
increased circulating HDL cholesterol level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Late adult	1.04x10^-5
improved glucose tolerance	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Late adult	2.38x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Early adult	2x10^-5
increased circulating total protein level	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Early adult	6.15x10^-5
increased bone mineral density	1 supporting dataset	Pitpnc1^{em1(IMPC)Kmpc}	homozygote	Late adult	6.52x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pitpnc1.

Associated images

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Histopathology

There is no histopathology data found for Pitpnc1.

IMPC related publications

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External links

No external links available for Pitpnc1.

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*Pitpnc1^{em1(IMPC)Kmpc}*	Indel	‌	mouse
*Pitpnc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pitpnc1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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