Marchf8 | membrane associated ring-CH-type finger 8

GeneMGI:1919029Synonyms: March8, Mir, +1 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Respiratory system Hematopoietic system Cardiovascular system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal heart morphology	2 supporting datasets	Marchf8^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Marchf8^{em2(IMPC)Ccpcz}	homozygote	Early adult	3.41x10^-8
increased airway resistance	1 supporting dataset	Marchf8^{em2(IMPC)Ccpcz}	homozygote	Early adult	6.9x10^-5
enlarged heart	2 supporting datasets	Marchf8^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased eosinophil cell number	1 supporting dataset	Marchf8^{em2(IMPC)Ccpcz}	homozygote	Early adult	1.46x10^-5
increased hematocrit	1 supporting dataset	Marchf8^{em2(IMPC)Ccpcz}	homozygote	Early adult	5.72x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Marchf8.

Associated images

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Histopathology

There is no histopathology data found for Marchf8.

IMPC related publications

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External links

No external links available for Marchf8.

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*Marchf8^{em2(IMPC)Ccpcz}*	Indel	‌	mouse
*Marchf8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Marchf8^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Marchf8^{tm33629(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Marchf8^{tm40908(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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