Bbs10 | Bardet-Biedl syndrome 10

GeneMGI:1919019Synonyms: 1300007O09Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
0Embryo tissues

Phenotypes

increased circulating sodium level1 supporting datasetBbs10tm1.1(KOMP)VlcgheterozygoteEarly adult3.61x10-6 
preweaning lethality, complete penetrance1 supporting datasetBbs10tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bbs10tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Bbs10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Bbs10tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Bbs10tm444900(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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