Ulk3 | unc-51-like kinase 3

GeneMGI:1918992Synonyms: 1200015E14Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Renal/urinary system

12 No significant impact

5 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating sodium level1 supporting datasetUlk3em2(IMPC)TcphomozygoteEarly adult4.12x10-9 
decreased circulating serum albumin level1 supporting datasetUlk3em2(IMPC)TcphomozygoteEarly adult7.6x10-6 
enlarged lymph nodes1 supporting datasetUlk3em2(IMPC)TcphomozygoteEarly adultN/A * 
enlarged prostate gland1 supporting datasetUlk3em2(IMPC)TcphomozygoteLate adultN/A * 
enlarged lymph nodes2 supporting datasetsUlk3em2(IMPC)TcphomozygoteLate adultN/A * 
abnormal spleen morphology1 supporting datasetUlk3em2(IMPC)TcphomozygoteEarly adultN/A * 
abnormal epididymis morphology1 supporting datasetUlk3em2(IMPC)TcphomozygoteLate adultN/A * 
abnormal uterus morphology1 supporting datasetUlk3em2(IMPC)TcphomozygoteLate adultN/A * 
small testis1 supporting datasetUlk3em2(IMPC)TcphomozygoteLate adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetUlk3em2(IMPC)TcphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ulk3em2(IMPC)TcpExon Deletionmouse

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