Dram1 | DNA-damage regulated autophagy modulator 1

GeneMGI:1918962Synonyms: 1200002N14Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Respiratory system Liver/biliary system Behavior/neurological

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal liver morphology	1 supporting dataset	Dram1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Dram1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.72x10^-5
abnormal lung morphology	1 supporting dataset	Dram1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dram1.

Associated images

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Histopathology

There is no histopathology data found for Dram1.

IMPC related publications

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External links

No external links available for Dram1.

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*Dram1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Dram1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Dram1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dram1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dram1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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