Optn | optineurin

GeneMGI:1918898Synonyms: TFIIIA-INTP, 4930441O07Rik

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Cardiovascular system

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

4Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



decreased heart weight	1 supporting dataset		Optn^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult		5.71x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Optn.

Associated images

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Histopathology

There is no histopathology data found for Optn.

IMPC related publications

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External links

No external links available for Optn.

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*Optn^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Optn^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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