Ythdf3 | YTH N6-methyladenosine RNA binding protein 3

GeneMGI:1918850Synonyms: 9130022A11Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Liver/biliary system Hematopoietic system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal thymus morphology1 supporting datasetYthdf3em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetYthdf3em1(IMPC)MbphomozygoteEarly adult9.97x10-6 
enlarged thymus1 supporting datasetYthdf3em1(IMPC)MbphomozygoteEarly adultN/A * 
small liver1 supporting datasetYthdf3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetYthdf3em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ythdf3em1(IMPC)MbpExon Deletionmouse
Ythdf3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ythdf3tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ythdf3tm3a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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