Arhgap21 | Rho GTPase activating protein 21
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Hearing/vestibular/ear Behavior/neurological Skeleton Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal auditory brainstem response | 3 supporting datasets | Arhgap21em1(IMPC)J | heterozygote | Early adult | 4.23x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Arhgap21em1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal vocalization | 1 supporting dataset | Arhgap21em1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| decreased bone mineral content | 1 supporting dataset | Arhgap21em1(IMPC)J | heterozygote | Early adult | 1.22x10-7 | ||
| abnormal body wall morphology | 1 supporting dataset | Arhgap21em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Arhgap21em1(IMPC)J | heterozygote | Early adult | 3.36x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Arhgap21em1(IMPC)J | heterozygote | Early adult | 5.11x10-6 |
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External links
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| Arhgap21em1(IMPC)J | Exon Deletion | | mouse |
| Arhgap21tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Arhgap21tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |