Ccdc57 | coiled-coil domain containing 57

GeneMGI:1918526Synonyms: 4933434G05Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hematopoietic system Skeleton Craniofacial

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased hematocrit	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.57x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.01x10^-13
decreased mean corpuscular volume	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.9x10^-18
decreased circulating potassium level	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.74x10^-5
abnormal cranium morphology	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.97x10^-5
decreased hemoglobin content	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.01x10^-5
decreased body weight	1 supporting dataset	Ccdc57^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.44x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccdc57.

Associated images

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Histopathology

There is no histopathology data found for Ccdc57.

IMPC related publications

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External links

No external links available for Ccdc57.

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*Ccdc57^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Ccdc57^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ccdc57^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Ccdc57^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Ccdc57^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Ccdc57^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Ccdc57^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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