Dlg5 | discs large MAGUK scaffold protein 5

GeneMGI:1918478Synonyms: 4933429D20Rik

Physiological systems

23 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Nervous system Vision/eye Craniofacial Mortality/aging Cardiovascular system

15 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

104Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hydrocephaly	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal brain morphology	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
spina bifida	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	heterozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	heterozygote	E15.5	N/A ^*
spina bifida	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Dlg5^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Dlg5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Dlg5.

Associated images

Loading...

Histopathology

There is no histopathology data found for Dlg5.

IMPC related publications

Loading...

External links

No external links available for Dlg5.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Dlg5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dlg5^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dlg5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes