Nbas | neuroblastoma amplified sequence

GeneMGI:1918419Synonyms: 4933425L03Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Adipose tissue Nervous system Vision/eye Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



persistence of hyaloid vascular system	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.17x10^-6
decreased total body fat amount	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.12x10^-5
abnormal vitreous body morphology	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.15x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.33x10^-10
abnormal retina blood vessel morphology	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.15x10^-7
abnormal retina vasculature morphology	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.23x10^-8
abnormal optic disk morphology	1 supporting dataset	Nbas^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.69x10^-16

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nbas.

Associated images

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Histopathology

There is no histopathology data found for Nbas.

IMPC related publications

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External links

No external links available for Nbas.

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*Nbas^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Nbas^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nbas^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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