Mier1 | MEIR1 treanscription regulator

GeneMGI:1918398Synonyms: 5830411K19Rik, 4933425I22Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



trunk curl	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.35x10^-12
decreased circulating free fatty acids level	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.25x10^-5
abnormal tail movements	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.08x10^-7
abnormal response to new environment	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.14x10^-7
decreased body weight	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.31x10^-10
abnormal behavior	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.64x10^-10
abnormal vocalization	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.51x10^-6
tremors	1 supporting dataset	Mier1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.47x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mier1.

Associated images

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Histopathology

There is no histopathology data found for Mier1.

IMPC related publications

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External links

No external links available for Mier1.

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*Mier1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mier1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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