Zfp689 | zinc finger protein 689

GeneMGI:1918381Synonyms: 4933416E05Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

thrombocytosis1 supporting datasetZfp689tm1.1(KOMP)VlcghomozygoteEarly adult6.32x10-5 
decreased hematocrit1 supporting datasetZfp689tm1.1(KOMP)VlcghomozygoteEarly adult4.7x10-8 
abnormal sleep behavior1 supporting datasetZfp689tm1.1(KOMP)VlcghomozygoteEarly adult4.04x10-5 
impaired righting response1 supporting datasetZfp689tm1.1(KOMP)VlcghomozygoteEarly adult4.66x10-5 
increased hemoglobin content1 supporting datasetZfp689tm1.1(KOMP)VlcghomozygoteEarly adult4.9x10-7 
preweaning lethality, incomplete penetrance1 supporting datasetZfp689tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp689tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Zfp689tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Zfp689tm47300(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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