Stx18 | syntaxin 18

GeneMGI:1918366Synonyms: 4933425D03Rik, 1810035L21Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Stx18^{tm2b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating glucose level	1 supporting dataset	Stx18^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	2.93x10^-7
embryonic lethality prior to tooth bud stage	1 supporting dataset	Stx18^{tm2b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Stx18^{tm2b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stx18.

Associated images

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Histopathology

There is no histopathology data found for Stx18.

IMPC related publications

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External links

No external links available for Stx18.

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*Stx18^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Stx18^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Stx18^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Stx18^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Stx18^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Stx18^{tm41896(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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