Nemf | nuclear export mediator factor
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Limbs/digits/tail Mortality/aging Cardiovascular system
16 No significant impact
3 Not tested
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
45Embryo tissues
| abnormal tail morphology | 1 supporting dataset | Nemftm1b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Nemftm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased circulating glucose level | 1 supporting dataset | Nemftm1b(EUCOMM)Hmgu | heterozygote | Early adult | 9.9x10-7 | ||
| decreased circulating cholesterol level | 1 supporting dataset | Nemftm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.05x10-6 | ||
| increased heart weight | 1 supporting dataset | Nemftm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.29x10-6 |
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External links
No external links available for Nemf.
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| Nemftm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Nemftm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Nemftm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |