Kctd1 | potassium channel tetramerisation domain containing 1

GeneMGI:1918269Synonyms: 4933402K10Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:22Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



eye hemorrhage	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	1.46x10^-5
decreased mean corpuscular volume	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	3.82x10^-13
increased circulating cholesterol level	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	7.67x10^-20
thrombocytopenia	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	4.12x10^-6
persistence of hyaloid vascular system	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	9.86x10^-13
increased circulating creatinine level	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	4.57x10^-39
increased circulating alkaline phosphatase level	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	1.75x10^-55
increased circulating bilirubin level	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	7.32x10^-5
increased circulating triglyceride level	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	1.76x10^-6
decreased bone mineral density	1 supporting dataset	Kctd1^em1(IMPC)J	homozygote	Early adult	2.93x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kctd1.

Associated images

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Histopathology

There is no histopathology data found for Kctd1.

IMPC related publications

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External links

No external links available for Kctd1.

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*Kctd1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Kctd1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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