Mex3b | mex3 RNA binding family member B

GeneMGI:1918252Synonyms: Rkhd3, 4931439A04Rik

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Craniofacial Renal/urinary system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:78Adult tissues

35Embryo tissues

Phenotypes

Phy. System:



increased freezing behavior	1 supporting dataset	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.2x10^-9
increased eosinophil cell number	2 supporting datasets	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.98x10^-6
abnormal kidney morphology	2 supporting datasets	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
vertebral transformation	1 supporting dataset	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.25x10^-9
abnormal ovary morphology	1 supporting dataset	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
hyperactivity	4 supporting datasets	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.03x10^-6
abnormal vertebral arch morphology	2 supporting datasets	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.05x10^-8
abnormal tooth morphology	1 supporting dataset	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal vertebrae morphology	1 supporting dataset	Mex3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.45x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mex3b.

Associated images

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Histopathology

There is no histopathology data found for Mex3b.

IMPC related publications

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External links

No external links available for Mex3b.

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*Mex3b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mex3b^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mex3b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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