Psd3 | pleckstrin and Sec7 domain containing 3

GeneMGI:1918215Synonyms: 4931420C21Rik, EFA6D

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased locomotor activity	3 supporting datasets	Psd3^em1(IMPC)H	homozygote	Late adult	3.92x10^-6
decreased circulating total protein level	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Early adult	1.2x10^-5
increased bone mineral density	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Late adult	1.2x10^-10
increased bone mineral content	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Late adult	1.08x10^-6
increased freezing behavior	2 supporting datasets	Psd3^em1(IMPC)H	homozygote	Late adult	1.73x10^-13
increased cardiac stroke volume	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Late adult	1.03x10^-10
increased cardiac output	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Late adult	1.29x10^-10
tremors	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Early adult	1.26x10^-7
impaired cued conditioning behavior	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Late adult	2.18x10^-6
prolonged QRS complex duration	1 supporting dataset	Psd3^em1(IMPC)H	homozygote	Early adult	7.43x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Psd3.

Associated images

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Histopathology

There is no histopathology data found for Psd3.

IMPC related publications

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External links

No external links available for Psd3.

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*Psd3^em1(IMPC)H*	Exon Deletion	‌	mouse
*Psd3^em2(IMPC)H*	Exon Deletion	‌	mouse

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