Dap | death-associated protein

GeneMGI:1918190Synonyms: 4921531N22Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Skeleton Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	1 supporting dataset	Dap^{tm1a(KOMP)Mbp}	homozygote	Early adult	7.5x10^-5
abnormal cornea morphology	1 supporting dataset	Dap^{tm1a(KOMP)Mbp}	homozygote	Early adult	2.56x10^-5
increased bone mineral content	1 supporting dataset	Dap^{tm1a(KOMP)Mbp}	homozygote	Early adult	5.33x10^-5
increased circulating free fatty acids level	1 supporting dataset	Dap^{tm1a(KOMP)Mbp}	homozygote	Early adult	4.17x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dap.

Associated images

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Histopathology

There is no histopathology data found for Dap.

IMPC related publications

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External links

No external links available for Dap.

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*Dap^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dap^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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