Setd2 | SET domain containing 2

GeneMGI:1918177Synonyms: KMT3A, 4921524K10Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Limbs/digits/tail Nervous system Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased exploration in new environment	1 supporting dataset	Setd2^{tm1b(NCOM)Mfgc}	homozygote	Early adult	9.18x10^-5
short tibia	1 supporting dataset	Setd2^{tm1b(NCOM)Mfgc}	homozygote	Early adult	7.21x10^-9
prolonged QRS complex duration	1 supporting dataset	Setd2^{tm1b(NCOM)Mfgc}	homozygote	Early adult	1.96x10^-5
decreased prepulse inhibition	2 supporting datasets	Setd2^{tm1b(NCOM)Mfgc}	homozygote	Early adult	3.36x10^-7
increased grip strength	1 supporting dataset	Setd2^{tm1b(NCOM)Mfgc}	homozygote	Early adult	9.87x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Setd2.

Associated images

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Histopathology

There is no histopathology data found for Setd2.

IMPC related publications

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External links

No external links available for Setd2.

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*Setd2^{tm1a(NCOM)Mfgc}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Setd2^{tm1b(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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