Cdkn2aip | CDKN2A interacting protein

GeneMGI:1918175Synonyms: 4921511I16Rik, CARF

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetCdkn2aipem1(IMPC)JhomozygoteEarly adult3.29x10-5 
increased startle reflex1 supporting datasetCdkn2aipem1(IMPC)JhomozygoteEarly adult1.61x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetCdkn2aipem1(IMPC)JhomozygoteEarly adultN/A * 
increased startle reflex1 supporting datasetCdkn2aipem1(IMPC)JheterozygoteEarly adult6.09x10-5 
increased blood urea nitrogen level1 supporting datasetCdkn2aipem1(IMPC)JhomozygoteEarly adult7.02x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdkn2aipem1(IMPC)JIntra-exon deletionmouse
Cdkn2aiptm96948(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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