Prdm5 | PR domain containing 5

GeneMGI:1918029Synonyms: 6530401I24Rik, 4432417F03Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Integument Endocrine/exocrine gland Nervous system Vision/eye Hearing/vestibular/ear Behavior/neurological

11 No significant impact

6 Not tested

Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal optic disk morphology1 supporting datasetPrdm5em1(IMPC)TcphomozygoteEarly adult1.5x10-5 
small testis1 supporting datasetPrdm5em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetPrdm5em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal auditory brainstem response3 supporting datasetsPrdm5em1(IMPC)TcphomozygoteEarly adult1.87x10-8 
decreased exploration in new environment1 supporting datasetPrdm5em1(IMPC)TcphomozygoteEarly adult8.2x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prdm5em1(IMPC)TcpIndelmouse
Prdm5tm362628(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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