Prpf3 | pre-mRNA processing factor 3

GeneMGI:1918017Synonyms: 3632413F13Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Prpf3^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Prpf3^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
increased neutrophil cell number	1 supporting dataset	Prpf3^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.52x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Prpf3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prpf3.

Associated images

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Histopathology

There is no histopathology data found for Prpf3.

IMPC related publications

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External links

No external links available for Prpf3.

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*Prpf3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Prpf3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Prpf3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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