Nos1ap | nitric oxide synthase 1 (neuronal) adaptor protein
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Skeleton Cardiovascular system Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
0Embryo tissues
| abnormal retina blood vessel morphology | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | 3.38x10-5 | ||
| decreased circulating alanine transaminase level | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | 8.49x10-7 | ||
| decreased bone mineral content | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | 2.9x10-6 | ||
| abnormal optic disk morphology | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | 6.17x10-6 | ||
| abnormal urinary bladder morphology | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased vertical activity | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | 2.02x10-5 | ||
| hyperactivity | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | homozygote | Early adult | 1.11x10-6 | ||
| tremors | 1 supporting dataset | Nos1aptm1b(KOMP)Wtsi | heterozygote | Early adult | 1.77x10-5 |
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External links
No external links available for Nos1ap.
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| Nos1aptm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Nos1aptm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |