Btbd7 | BTB domain containing 7

GeneMGI:1917858Synonyms: FUP1, 5730507E09Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Respiratory system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased lung compliance2 supporting datasetsBtbd7em1(IMPC)CcpczhomozygoteEarly adult2.4x10-5 
decreased lung elastance6 supporting datasetsBtbd7em1(IMPC)CcpczhomozygoteEarly adult6.54x10-7 
enlarged spleen1 supporting datasetBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal eye morphology2 supporting datasetsBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal inspiratory capacity2 supporting datasetsBtbd7em1(IMPC)CcpczhomozygoteEarly adult2.11x10-7 
enlarged heart1 supporting datasetBtbd7em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Btbd7em1(IMPC)CcpczExon Deletionmouse
Btbd7tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Btbd7tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Btbd7tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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