Dnajb14 | DnaJ heat shock protein family (Hsp40) member B14

GeneMGI:1917854Synonyms: 5730496F10Rik

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Hematopoietic system Skeleton Mortality/aging

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



increased mean corpuscular volume	1 supporting dataset	Dnajb14^em1(IMPC)J	heterozygote	Early adult	5.84x10^-5
abnormal body wall morphology	1 supporting dataset	Dnajb14^em1(IMPC)J	homozygote	E18.5	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Dnajb14^{em1(IMPC)Hmgu}	heterozygote	Early adult	3.07x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Dnajb14^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal bone structure	1 supporting dataset	Dnajb14^em1(IMPC)J	heterozygote	Early adult	1.21x10^-6
increased circulating phosphate level	1 supporting dataset	Dnajb14^em1(IMPC)J	heterozygote	Early adult	8.88x10^-6
abnormal auditory brainstem response	2 supporting datasets	Dnajb14^em1(IMPC)J	heterozygote	Early adult	6.29x10^-6
decreased bone mineral content	1 supporting dataset	Dnajb14^em1(IMPC)J	heterozygote	Early adult	1.1x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Dnajb14^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnajb14.

Associated images

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Histopathology

There is no histopathology data found for Dnajb14.

IMPC related publications

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External links

No external links available for Dnajb14.

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*Dnajb14^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Dnajb14^em1(IMPC)J*	Exon Deletion	‌	mouse
*Dnajb14^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Dnajb14^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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