Eef2kmt | eukaryotic elongation factor 2 lysine methyltransferase

GeneMGI:1917761Synonyms: Fam86, 5730409G15Rik

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Respiratory system Behavior/neurological

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

impaired glucose tolerance1 supporting datasetEef2kmttm1b(EUCOMM)WtsihomozygoteEarly adult5.67x10-5 
increased pulmonary respiratory rate1 supporting datasetEef2kmttm1b(EUCOMM)WtsihomozygoteEarly adult3.64x10-23 
abnormal response to tactile stimuli1 supporting datasetEef2kmttm1e(EUCOMM)WtsihomozygoteEarly adult3.53x10-6 
increased grip strength1 supporting datasetEef2kmttm1e(EUCOMM)WtsihomozygoteEarly adult4.42x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eef2kmttm46166(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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