2810408A11Rik | RIKEN cDNA 2810408A11 gene

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased CD4-positive, alpha-beta T cell number1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult1.34x10-6 
decreased erythrocyte cell number1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult6.57x10-5 
increased mean corpuscular hemoglobin concentration1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult4.53x10-5 
abnormal bone structure1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult4.01x10-5 
increased lean body mass1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult6.87x10-5 
limb grasping1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult5.47x10-9 
increased heart weight1 supporting dataset2810408A11Riktm1a(EUCOMM)WtsihomozygoteEarly adult1.54x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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2810408A11Riktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
2810408A11Riktm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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