Stk26 | serine/threonine kinase 26

GeneMGI:1917665Synonyms: 2610018G03Rik, Mst4

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:156Adult tissues

72Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased monocyte cell number	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.03x10^-5
abnormal adrenal gland morphology	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal thyroid gland morphology	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	N/A ^*
decreased mean platelet volume	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	1.28x10^-5
decreased circulating creatinine level	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.52x10^-11
enlarged thyroid gland	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	N/A ^*
abnormal pancreas morphology	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	N/A ^*
enlarged adrenal glands	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
enlarged pancreas	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	N/A ^*
decreased mean platelet volume	1 supporting dataset	Stk26^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.47x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stk26.

Associated images

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Histopathology

There is no histopathology data found for Stk26.

IMPC related publications

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External links

No external links available for Stk26.

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*Stk26^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Stk26^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Stk26^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Stk26^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Stk26^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Stk26^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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