Ptges2 | prostaglandin E synthase 2

GeneMGI:1917592Synonyms: 0610038H10Rik, GBF-1, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

17 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

thrombocytosis1 supporting datasetPtges2tm1a(EUCOMM)WtsihomozygoteEarly adult1.84x10-5 
decreased circulating chloride level1 supporting datasetPtges2tm1a(EUCOMM)WtsihomozygoteEarly adult2.13x10-5 
increased circulating alkaline phosphatase level1 supporting datasetPtges2tm1a(EUCOMM)WtsihomozygoteEarly adult7.84x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptges2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ptges2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ptges2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Ptges2tm3a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ptges2tm3e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Ptges2tm96746(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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