Bclaf1 | BCL2-associated transcription factor 1

GeneMGI:1917580Synonyms: 2700025J07Rik, 2810454G14Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hyperactivity	1 supporting dataset	Bclaf1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.98x10^-5
cyanosis	1 supporting dataset	Bclaf1^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
decreased grip strength	1 supporting dataset	Bclaf1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.96x10^-5
abnormal lens morphology	1 supporting dataset	Bclaf1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.04x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Bclaf1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bclaf1.

Associated images

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Histopathology

There is no histopathology data found for Bclaf1.

IMPC related publications

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External links

No external links available for Bclaf1.

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*Bclaf1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Bclaf1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Bclaf1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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