Skic8 | SKI8 subunit of superkiller complex
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Adipose tissue Vision/eye Hematopoietic system Cardiovascular system Mortality/aging
12 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Skic8em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Skic8em1(IMPC)Tcp | heterozygote | Early adult | 4.75x10-5 | ||
| enlarged lymph nodes | 1 supporting dataset | Skic8em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Skic8em1(IMPC)Tcp | heterozygote | Early adult | 4.13x10-5 | ||
| increased monocyte cell number | 1 supporting dataset | Skic8em1(IMPC)Tcp | heterozygote | Early adult | 6.4x10-6 | ||
| abnormal spleen morphology | 1 supporting dataset | Skic8em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Skic8em1(IMPC)Tcp | heterozygote | Early adult | 4.58x10-5 |
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External links
No external links available for Skic8.
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| Skic8em1(IMPC)Tcp | Exon Deletion | | mouse |
| Skic8tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Skic8tm45573(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Skic8tm45573(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |