Poc1a | POC1 centriolar protein A

GeneMGI:1917485Synonyms: cha, Wdr51a, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Mortality/aging Renal/urinary system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased urine microalbumin level	1 supporting dataset	Poc1a^{tm1.1(KOMP)Mbp}	heterozygote	Early adult	2.58x10^-23
female infertility	1 supporting dataset	Poc1a^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Poc1a^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Poc1a^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
decreased fasting circulating glucose level	1 supporting dataset	Poc1a^{tm1.1(KOMP)Mbp}	heterozygote	Early adult	2.05x10^-17

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Poc1a.

Associated images

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Histopathology

There is no histopathology data found for Poc1a.

IMPC related publications

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External links

No external links available for Poc1a.

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*Poc1a^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Poc1a^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Poc1a^{tm450483(L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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