Taco1 | translational activator of mitochondrially encoded cytochrome c oxidase I
Physiological systems
17 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Growth/size/body region Vision/eye Behavior/neurological Mortality/aging Cardiovascular system
10 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating creatinine level | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Late adult | 4.12x10-8 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased heart weight | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Early adult | 2.52x10-5 | ||
| iris synechia | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Early adult | 7.47x10-5 | ||
| abnormal coat/ hair morphology | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Late adult | 6.68x10-5 | ||
| increased grip strength | 1 supporting dataset | Taco1em1(IMPC)J | heterozygote | Late adult | 2.54x10-5 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Late adult | 2.23x10-6 | ||
| abnormal skin morphology | 1 supporting dataset | Taco1em1(IMPC)J | homozygote | Early adult | 1.57x10-5 |
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External links
No external links available for Taco1.
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| Taco1em1(IMPC)J | Exon Deletion | | mouse |
| Taco1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Taco1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Taco1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |