Abhd17c | abhydrolase domain containing 17C

GeneMGI:1917428Synonyms: 2210412D01Rik, Fam108c

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal heart morphology	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	9.26x10^-5
small kidney	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
microphthalmia	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
decreased circulating alanine transaminase level	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	2.95x10^-5
abnormal kidney morphology	1 supporting dataset	Abhd17c^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abhd17c.

Associated images

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Histopathology

There is no histopathology data found for Abhd17c.

IMPC related publications

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External links

No external links available for Abhd17c.

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*Abhd17c^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Abhd17c^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Abhd17c^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Abhd17c^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Abhd17c^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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