Dpf3 | double PHD fingers 3

GeneMGI:1917377Synonyms: 2810403B03Rik, Gm18872, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition1 supporting datasetDpf3em1(IMPC)JhomozygoteEarly adult9.88x10-10 
decreased circulating calcium level1 supporting datasetDpf3em1(IMPC)JhomozygoteEarly adult1.7x10-5 
decreased grip strength1 supporting datasetDpf3em1(IMPC)JhomozygoteEarly adult6.25x10-5 
decreased locomotor activity1 supporting datasetDpf3em1(IMPC)JhomozygoteEarly adult9.62x10-7 
decreased bone mineral content1 supporting datasetDpf3em1(IMPC)JhomozygoteEarly adult1.06x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dpf3em1(IMPC)JExon Deletionmouse
Dpf3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dpf3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dpf3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Dpf3tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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