Sash1 | SAM and SH3 domain containing 1
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Skeleton Mortality/aging Cardiovascular system
15 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Sash1em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Sash1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Sash1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| increased bone mineral content | 2 supporting datasets | Sash1em1(IMPC)Bay | heterozygote | Early adult | 2.84x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Sash1em1(IMPC)Bay | heterozygote | E18.5 | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Sash1em1(IMPC)Bay | heterozygote | Early adult | 8.67x10-5 |
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External links
No external links available for Sash1.
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| Sash1em1(IMPC)Bay | Exon Deletion | | mouse |
| Sash1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sash1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |