Trnt1 | tRNA nucleotidyl transferase, CCA-adding, 1

GeneMGI:1917297Synonyms: 2610044E04Rik, CGI-47, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Growth/size/body region Vision/eye Hematopoietic system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased body weight1 supporting datasetTrnt1tm1a(EUCOMM)HmguheterozygoteEarly adult9.36x10-11 
abnormal retina pigmentation2 supporting datasetsTrnt1tm1a(EUCOMM)HmguheterozygoteEarly adult4.48x10-7 
increased circulating glucose level1 supporting datasetTrnt1tm1a(EUCOMM)HmguheterozygoteEarly adult7.32x10-5 
decreased mean corpuscular volume1 supporting datasetTrnt1tm1a(EUCOMM)HmguheterozygoteEarly adult2.46x10-5 
abnormal eye morphology1 supporting datasetTrnt1tm1a(EUCOMM)HmguheterozygoteEarly adult2.75x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trnt1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trnt1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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