Kat14 | lysine acetyltransferase 14

GeneMGI:1917264Synonyms: ATAC2, 2510008M08Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Growth/size/body region Vision/eye Hematopoietic system Skeleton Craniofacial Mortality/aging Cardiovascular system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:22Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal eye pigmentation	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.9x10^-6
increased circulating magnesium level	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.84x10^-6
abnormal eye morphology	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.46x10^-5
abnormal pupil morphology	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.04x10^-7
decreased body weight	4 supporting datasets	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.81x10^-7
abnormal cornea morphology	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.17x10^-8
abnormal eye size	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.78x10^-10
decreased body length	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.26x10^-5
cornea opacity	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.2x10^-6
increased circulating creatine kinase level	1 supporting dataset	Kat14^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.63x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kat14.

Associated images

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Histopathology

There is no histopathology data found for Kat14.

IMPC related publications

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External links

No external links available for Kat14.

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*Kat14^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Kat14^{tm285808(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Kat14^{tm35277(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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