Galk2 | galactokinase 2

GeneMGI:1917226Synonyms: 2810017M24Rik, Gk2

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Vision/eye Behavior/neurological Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased grip strength	2 supporting datasets	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.27x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.28x10^-5
abnormal vitreous body morphology	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.88x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.26x10^-10
abnormal retina blood vessel morphology	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.7x10^-6
abnormal digit morphology	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.63x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.25x10^-8
increased circulating bilirubin level	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.74x10^-5
abnormal lens morphology	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.65x10^-11
cardiovascular system phenotype	1 supporting dataset	Galk2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.98x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Galk2.

Associated images

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Histopathology

There is no histopathology data found for Galk2.

IMPC related publications

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External links

No external links available for Galk2.

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*Galk2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Galk2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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